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MYP_123022
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Basic Information
Hp1404-T1a
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C68H116N16O16
Standard
Sequence
ILKKLWEGVKSI
Physicochemical Analysis
1413.75 Da
9.70
1.76
1.55
0.1467
0.29
0.70
0.15
28.40
154.17
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
534.80
-0.83
19.0
18.0
50.0
100.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0253097 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa 5018
25 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0253305 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa 671973
25 μM
MIC
PaperMechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa. Sci Rep. 2018 Jan 29;8(1):1763. doi: 10.1038/s41598-018-19434-7. PMID: 29379033. PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0262461 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa 3399
25 μM
MIC
PaperMechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa. Sci Rep. 2018 Jan 29;8(1):1763. doi: 10.1038/s41598-018-19434-7. PMID: 29379033. PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0291772 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa 559
25 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0299076 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa 4891
25 μM
MIC
PaperMechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa. Sci Rep. 2018 Jan 29;8(1):1763. doi: 10.1038/s41598-018-19434-7. PMID: 29379033. PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
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