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MYP_123022
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Basic Information
Hp1404-T1a
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C68H116N16O16
Standard
Sequence
ILKKLWEGVKSI
Physicochemical Analysis
1413.75 Da
9.70
1.76
1.55
0.1467
0.29
0.70
0.15
28.40
154.17
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
534.80
-0.83
19.0
18.0
50.0
100.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0064081 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa 4007
25 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0075848 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa 3592
12.5 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0106028 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa 3543
25 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0111283 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
25 μM
MIC
PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
RECORD: Rec_0115956 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa 434
25 μM
MIC
PaperMechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa. Sci Rep. 2018 Jan 29;8(1):1763. doi: 10.1038/s41598-018-19434-7. PMID: 29379033. PMID29379033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29379033/
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