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MYP_123012
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Basic Information
Casozepine
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
7 amino acids
C42H60N8O13
Standard
Sequence
YLGYLEQ
Physicochemical Analysis
884.97 Da
4.05
-1.24
-1.45
-0.1770
-0.34
0.32
0.22
23.96
111.43
0.2857
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
358.77
-0.94
12.0
12.0
27.0
63.0
2.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036486 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casozepine
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anxiolytic
PaperIn Vitro Digestibility of r-Casozepine, a Benzodiazepine-like Peptide from Bovine Casein, and Biological Activity of Its Main Proteolytic Fragment | Cakir-Kiefer, C. et al. | DOI: 10.1021/jf104089c Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0262418 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casozepine
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anxiolytic
Caco-2 cells
PaperTransport Across Caco-2 Cell Monolayer and Sensitivity to Hydrolysis of Two Anxiolytic Peptides from αs1-Casein, α-Casozepine, and αs1-Casein-(f91-97): Effect of Bile Salts | Cakir-Kiefer, C. et al. | DOI: 10.1021/jf202890e Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0362109 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
PaperCakir-Kiefer C., Le Roux Y., Balandras F., Trabalon M., Dary A., Laurent F., Gaillard J. L., Miclo L.. In vitro digestibility of alpha-casozepine, a benzodiazepine-like peptide from bovine casein, and biological activity of its main proteolytic fragment. J. Agric. Food Chem., 59, 4464-4472, 2011.