Peptide Database

Peptide NameColicin pyocin immunity family protein (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length903 amino acids

Chemical FormulaC4399H6850N1234O1298S17

DescriptionStandard

        MGEGHSNVTGHGGRGPTGGVKGGPTGFGGGNPNSGKGWGVSQTPYGPLHNYNPGKFGNSHSSRGNRGGGHNAGHRGNSPNLSEKPELQVAIVPGIAVPLTLVASEWGFTLYNPKLVAAAMDAAFSRLAVVAMDAAPYVGRFAGIVGMMLVPSEIAKDDMSVTRRTVVTLPADRITTMPFAQLPTQPAVVANTRLHDMVQDGMQKIALVKSNNVPATVPVVQAKPTVRPGVFTAQILHGMPPIHIHVETQSPPPATLPAKGINEVKDAPVIAVSSPLGNHSHDAIVYFPPEAKTDPVYISVTTLLTPEQIRQQEDEDRRKQAAWEASYPIEAAENLLSIANDALRREQHNVYPFQAVLDEFKNSWEGQLLTDPEGHPFNEDFEEYYYLSMNYRYQFVYNIKVENRQDLDKLLTIGGEAFDPFPNGITQEDLDFFKDEHPALIMQALIIEEYNLLRQHLLAHQAKIHVAQTALNSAQHQLNMAQDEVNNAEQHLIQAKVQRVHAENARLAVEAAERRRIVEEQQAAEEVERQRIVHQNTFFLPAHPIRSRYSAGFSIADKGAITLASPAIQGLSTSLSAALAKFRTIAVSSLAVPIAAIIGAGFYPSNTGQSGAPSPLAGSIALSEMGLSATTPLPLEGEIDLPARMVMANTRNTTVFWAVKTGIAGITSKVKAGVAQFDRSTGVYTFTTDSLPPRTFTFTPVRPSGSEVRWVFPNPANVPVLPLNTGIDIEHVASPLVLPQPLLQEGHFHDYIIWFPADSGLQPVYIYLNSPRNEPGVVTGHGEPIFGNWLAEAGKGLGAPIPSQIADKLRGQEFSSFDKFRETFWREVSQDPELAGQFNKINRSIMRNGISPFPPKKEHVGGREKYEIHHVNPINGGGAVYDIDNLRVVTPKRHIEIHTRNGV
    

Molecular Weight98336.04 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-9.57

Net Charge (pH 7.4) -11.61

Charge Density (pH 7.0) -0.0106

GRAVY Index-0.27

Hydrophobic Moment 0.84

Boman Index0.06

Instability Index46.66

Aliphatic Index 83.62

Aromaticity 0.0764

Extinction Coeff. Reduced 83770.00

Extinction Coeff. Oxidized 83770.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174860 VERIFIED: NO

Provenance & Taxonomy

OrganismYersinia frederiksenii [Bacterium]

FamilyColicin pyosin nuclease

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli