Peptide Database

Peptide NameIFN-α6

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length169 amino acids

Chemical FormulaC886H1394N250O262S10

DescriptionStandard

        SLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFRFPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLEACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRNLQERLRRKE
    

Molecular Weight20060.71 Da

Isoelectric Point (pI)6.43

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.71

Charge Density (pH 7.0) -0.0070

GRAVY Index-0.49

Hydrophobic Moment 0.68

Boman Index-0.12

Instability Index55.76

Aliphatic Index 82.49

Aromaticity 0.1006

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24200.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8389.65

LogP -84.53

H-bond Donors 298.0

H-bond Acceptors 275.0

Rotatable Bonds 682.0

Heavy Atoms 1408.0

Ring Count 28.0

Amide Bonds 185.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0015317 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 4 and 102, and 32 and 142

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)