Peptide Database

Peptide Name3G-Cathelicidin-6 (8-27)[F7C, L14C]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC115H198N32O26S2

DescriptionStandard

        GGGGKKCKKLFKKCSPVIPLLHLG
    

Molecular Weight2509.13 Da

Isoelectric Point (pI)10.05

Net Charge (pH 7.0)5.82

Net Charge (pH 7.4) 5.53

Charge Density (pH 7.0) 0.2426

GRAVY Index-0.04

Hydrophobic Moment 0.69

Boman Index0.06

Instability Index36.80

Aliphatic Index 93.33

Aromaticity 0.0417

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 920.07

LogP -6.56

H-bond Donors 33.0

H-bond Acceptors 35.0

Rotatable Bonds 87.0

Heavy Atoms 175.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097435 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli 1

Activity2.7 μM

MethodMIC

RECORD: Rec_0148881 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa

Activity16 μM

MethodMIC

RECORD: Rec_0179032 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa 1

Activity27 μM

MethodMIC

RECORD: Rec_0181453 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli

Activity1.3 μM

MethodMIC

RECORD: Rec_0381389 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familycathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetSheep erythrocytes

Activity>32 μM

MethodHemolysis