Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC423H669N119O123S13

DescriptionStandard

        MKAFSIAVAVTLVLAFICVVQSSAVPFTGVGELEEAGGNDTPVEAHQEVSMESWMMPKHVREKRQSHLSLCRYCCNCCKNKGCGFCCRF
    

Molecular Weight9806.41 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0077

GRAVY Index0.15

Hydrophobic Moment 0.57

Boman Index0.08

Instability Index43.28

Aliphatic Index 71.12

Aromaticity 0.0787

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3856.75

LogP -39.71

H-bond Donors 142.0

H-bond Acceptors 140.0

Rotatable Bonds 323.0

Heavy Atoms 678.0

Ring Count 14.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022426 VERIFIED: NO

Provenance & Taxonomy

OrganismXiphophorus couchianus [Bacterium]

FamilyHepcidin

Tax ID32473

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal

RECORD: Rec_0238237 VERIFIED: NO