Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC545H875N143O168S5

DescriptionStandard

        PDLSGYEKFGLGNVKYNISRIHVTAVEFPSASISLMPGTGIKLVIENASLTIDMSWNIRTWMFKDSGRSTVCISKVFVTAIFSVPLDNTGSASISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12278.96 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.87

Charge Density (pH 7.0) 0.0178

GRAVY Index0.14

Hydrophobic Moment 0.53

Boman Index0.13

Instability Index31.89

Aliphatic Index 93.16

Aromaticity 0.0789

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4982.17

LogP -55.95

H-bond Donors 180.0

H-bond Acceptors 176.0

Rotatable Bonds 407.0

Heavy Atoms 861.0

Ring Count 16.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409117 VERIFIED: NO

Provenance & Taxonomy

OrganismAtlantisia rogersi [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria