Peptide Database

Peptide NameEPYLRFamide

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC40H57N9O10

DescriptionStandard

        EPYLRF
    

Molecular Weight823.93 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-0.16

Net Charge (pH 7.4) -0.34

Charge Density (pH 7.0) -0.0274

GRAVY Index-0.72

Hydrophobic Moment 0.63

Boman Index-0.11

Instability Index72.53

Aliphatic Index 65.00

Aromaticity 0.3333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 319.46

LogP -0.31

H-bond Donors 11.0

H-bond Acceptors 10.0

Rotatable Bonds 23.0

Heavy Atoms 59.0

Ring Count 3.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124489 VERIFIED: YES

Provenance & Taxonomy

OrganismUnknown [Animal]

FamilyEPYLRFamide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor modulation ACE inhibitory

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0271742 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide related peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0409559 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/