Peptide Database

Peptide NameNatriuretic peptide PaNP-b

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC154H251N49O50S2

DescriptionStandard

        SDSKIGDGCFGLPLDHIGSVSGLGCNRPVQNRPKQ
    

Molecular Weight3653.07 Da

Isoelectric Point (pI)7.81

Net Charge (pH 7.0)0.53

Net Charge (pH 7.4) 0.24

Charge Density (pH 7.0) 0.0151

GRAVY Index-0.52

Hydrophobic Moment 0.42

Boman Index-0.06

Instability Index54.11

Aliphatic Index 72.29

Aromaticity 0.0286

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1596.05

LogP -21.74

H-bond Donors 55.0

H-bond Acceptors 54.0

Rotatable Bonds 120.0

Heavy Atoms 255.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050224 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudechis australis [Animal]

FamilyNatriuretic peptide PaNP

Tax ID8670

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide9-25

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0309930 VERIFIED: YES