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MYP_122869
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Basic Information
Mucroporin-M1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-H5N1
Antiviral ▸ Antiviral mechanism ▸ Pseudovirus inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Antiviral ▸ Virucidal activity
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C98H170N26O20
Standard
Sequence
LFRLIKSLIKRLVSAFK
Physicochemical Analysis
2032.56 Da
12.00
4.76
4.55
0.2798
0.79
0.88
0.07
9.76
160.59
0.1176
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
771.24
-2.51
29.0
25.0
72.0
144.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0360579 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Measles virus
7.15 μg/mL
EC50
PMID26492266;21620914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26492266/
RECORD: Rec_0367130 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic Anticancer
HeLa-ACE2 cells
61
CC50
PaperPubMed PMID: 21620914 PMID21620914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21620914/
RECORD: Rec_0369882 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
SARS-CoV
14.46 μg/mL
EC50
PMID26492266;21620914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26492266/
RECORD: Rec_0412682 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
Vero cells
70
CC50
PaperPubMed PMID: 21620914 PMID21620914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21620914/
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