Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC234H368N68O57

DescriptionStandard

        PPLRYSPPGQRVIPPPADERFLRFLVFHLNKIRIRAREIYES
    

Molecular Weight5045.85 Da

Isoelectric Point (pI)10.80

Net Charge (pH 7.0)4.05

Net Charge (pH 7.4) 3.93

Charge Density (pH 7.0) 0.0965

GRAVY Index-0.52

Hydrophobic Moment 0.60

Boman Index-0.15

Instability Index58.81

Aliphatic Index 92.86

Aromaticity 0.1190

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1993.99

LogP -13.15

H-bond Donors 70.0

H-bond Acceptors 62.0

Rotatable Bonds 157.0

Heavy Atoms 359.0

Ring Count 13.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288070 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0359942 VERIFIED: YES

Provenance & Taxonomy

OrganismConus [Animal]

FamilyConotoxin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Replication inhibitor

TargetInfluenza A virus (Nucleoprotein); 293T

MethodLuciferase assay

PaperInhibition of influenza virus replication by constrained peptides targeting nucleoprotein. | Jiang H, Xu Y, Li L, Weng L, Wang Q, Zhang S, Jia B, Hu H, He Y, Jacob Y, Toyoda T. | Antivir Chem Chemother. 2011 | PMID:22095520 PMID22095520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22095520/