Peptide Database

Peptide NameSmall hydrophobic peptide-1- LLL

Function Ontology

Antimicrobial

Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC74H114N20O21

DescriptionStandard

        SDLGAVISWGRQLFA
    

Molecular Weight1619.82 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0359

GRAVY Index0.53

Hydrophobic Moment 0.47

Boman Index0.28

Instability Index9.60

Aliphatic Index 110.67

Aromaticity 0.1333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 669.26

LogP -5.76

H-bond Donors 24.0

H-bond Acceptors 21.0

Rotatable Bonds 51.0

Heavy Atoms 115.0

Ring Count 3.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096904 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilySynthetic peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antitrypanosomal Antiparasitic

TargetTrypanosoma brucei brucei Lister 427 (MiTat 1.2)

Activity~10 μM

MethodMicroscopy (Trypan blue dye viability assay)

RECORD: Rec_0353238 VERIFIED: YES