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MYP_122795
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Basic Information
Tracheal antimicrobial peptide (TAP)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
64 amino acids
C306H515N93O75S8
Standard
Sequence
MRLHHLLLALLFLVLSAWSGFTQGVGNPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK
Physicochemical Analysis
6953.46 Da
10.26
9.61
9.20
0.1502
0.43
0.69
0.11
18.54
103.44
0.0469
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2676.74
-24.76
101.0
95.0
231.0
482.0
9.0
67.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070092 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Beta-defensin; Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Candida albicans
PMID2023943;8506305 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2023943/
RECORD: Rec_0099582 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Beta-defensin; Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli
PMID2023943;8506305 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2023943/
RECORD: Rec_0143248 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Beta-defensin; Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Pseudomonas
PMID2023943;8506305 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2023943/
RECORD: Rec_0209413 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ7250
RECORD: Rec_0359555 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6399370 B1 Evidence URLhttps://patents.google.com/patent/US6399370B1/en PatentUS 6399370 B1
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