Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC561H890N148O169S4

DescriptionStandard

        PDLSGYEKYGLGNVKYNISRIHVTAVEFPSASIFLMPGTGIKLVIENASLTIDMNWNIRTWMFKDNGRSTVYISKVFVTAILSTPLDNTGHTSISLTSCRTTSGDIDIKLHGKS
    

Molecular Weight12540.22 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)2.21

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index-0.02

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index22.46

Aliphatic Index 93.16

Aromaticity 0.0877

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5082.62

LogP -53.26

H-bond Donors 182.0

H-bond Acceptors 178.0

Rotatable Bonds 413.0

Heavy Atoms 882.0

Ring Count 19.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0150407 VERIFIED: NO

Provenance & Taxonomy

OrganismNyctiprogne leucopyga [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria