Peptide Database

Peptide NameTurkey Heterophil Peptide 2 (Antimicrobial peptide THP2, THP2; Birds, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC185H274N54O43S6

DescriptionStandard

        LFCKRGTCHFGRCPSHLIKVGSCFGFRSCCKWPWDA
    

Molecular Weight4134.88 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)4.87

Net Charge (pH 7.4) 4.48

Charge Density (pH 7.0) 0.1354

GRAVY Index-0.01

Hydrophobic Moment 0.67

Boman Index0.03

Instability Index53.38

Aliphatic Index 43.33

Aromaticity 0.1667

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1535.16

LogP -13.34

H-bond Donors 62.0

H-bond Acceptors 56.0

Rotatable Bonds 128.0

Heavy Atoms 288.0

Ring Count 12.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299298 VERIFIED: YES

Provenance & Taxonomy

OrganismMeleagris gallopavo [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0419573 VERIFIED: YES

Provenance & Taxonomy

OrganismWild turkey [Animal]; Animalia [Animal]

Tax ID33208; 33208