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MYP_122752
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Basic Information
Unnamed
Antimicrobial
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C20H32N4O4
Standard
Sequence
VKF
Physicochemical Analysis
392.49 Da
8.72
0.73
0.52
0.2443
1.03
0.63
0.26
-2.93
96.67
0.3333
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
147.54
0.40
5.0
5.0
12.0
28.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070001 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0078310 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
11.0
PaperQi C., Lin G., Zhang R., Wu W.. Studies on the bioactivities of ACE-inhibitory Peptides with phenylalanine C-terminus Using 3D-QSAR, molecular docking and in vitro evaluation. Mol Inform. 36, 1600157, 2017.
RECORD: Rec_0251982 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: (3¦Á,5¦Â,7¦Á,12¦Á)-3,7,12-Triaminocholan-24-ol
Bio-Activity Profile
Antimicrobial
PaperSynthesis and Characterization of Peptide-Cationic Steroid Antibiotic Conjugates. Organic Letters. 2004 Evidence URLhttps://doi.org/10.1021/ol048845t
RECORD: Rec_0284377 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1029 μM
IC50
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
RECORD: Rec_0310210 VERIFIED: YES
Provenance & Taxonomy
Mactra veneriformis [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
10.4 μM
IC50
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