Peptide Database

Peptide NameBeta-defensin 1 (BD-1) (Defensin; beta 1)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC323H510N86O94S10

DescriptionStandard

        MRTSYLLLFILCLVLCDMDSGDTFLTGLGHRSDHYNCVKGGGQCLYSACPIYTKVQGTCYGGKAKCCK
    

Molecular Weight7422.67 Da

Isoelectric Point (pI)8.45

Net Charge (pH 7.0)2.59

Net Charge (pH 7.4) 2.14

Charge Density (pH 7.0) 0.0381

GRAVY Index0.16

Hydrophobic Moment 0.45

Boman Index0.12

Instability Index38.37

Aliphatic Index 78.82

Aromaticity 0.1029

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2877.18

LogP -28.96

H-bond Donors 110.0

H-bond Acceptors 109.0

Rotatable Bonds 244.0

Heavy Atoms 513.0

Ring Count 10.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152385 VERIFIED: YES

Provenance & Taxonomy

OrganismSaguinus oedipus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic