‹ ›
MYP_122695
← PREVIOUS NEXT → BACK
Basic Information
Las[des15-27, Ala8]-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C70H131N21O15
Standard
Sequence
GLPRKILAAIAKKK
Physicochemical Analysis
1506.92 Da
11.33
4.76
4.55
0.3397
-0.01
0.59
-0.09
25.35
132.86
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
598.81
-3.14
21.0
20.0
54.0
106.0
1.0
13.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0142254 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
100 μM
MIC
PMID22038181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038181/
RECORD: Rec_0171569 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Hemolytic activity
200 μM
LC50
PMID22038181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038181/
RECORD: Rec_0274004 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
200 μM
Hemolysis
PaperMonincová L, Slaninová J, Fučík V, et al. Lasiocepsin, a novel cyclic antimicrobial peptide from the venom of eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). Amino Acids. 2012 Aug;43(2):751-761. doi:10.1007/s00726-011-1125-6. PMID22038181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038181/
RECORD: Rec_0317013 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
100 μM
MIC
PMID22038181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038181/
RECORD: Rec_0324448 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
100 μM
MIC
PMID22038181 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22038181/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2