Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC91H143N27O33S4

DescriptionStandard

        GIVEQCCHNTCSLANLEGYCN
    

Molecular Weight2271.53 Da

Isoelectric Point (pI)4.51

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.1042

GRAVY Index0.01

Hydrophobic Moment 0.32

Boman Index0.11

Instability Index25.73

Aliphatic Index 74.29

Aromaticity 0.0476

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 981.65

LogP -13.20

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 73.0

Heavy Atoms 155.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075811 VERIFIED: YES

Provenance & Taxonomy

OrganismChimaera monstrosa [Animal]

FamilyInsulin

Tax ID7871

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0336550 VERIFIED: YES