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MYP_122645
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Basic Information
Oxytocin
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Lactation-associated neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Therapeutic / Biomedical activity ▸ Enzyme replacement therapy
Standard
9 amino acids
C43H67N11O13S2
Standard
Sequence
CYIQNCPLG
Physicochemical Analysis
1010.19 Da
5.51
-0.26
-0.49
-0.0290
0.33
0.14
0.25
27.09
86.67
0.1111
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
393.74
-3.54
14.0
15.0
29.0
69.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0274893 VERIFIED: YES
Provenance & Taxonomy
Balaenoptera physalus [Animal]
Oxytocin
9770
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Myotropic
causes contraction of the smooth muscle
Experimental: 6.78 minutes; /406.8 seconds; Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Oxytocin (Balaenoptera physalus): PMID 14118277##10454085 PMID14118277;10454085 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14118277/
RECORD: Rec_0291553 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Oxytocin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Blocked
Amidation
Bio-Activity Profile
Hormone
RECORD: Rec_0298334 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Oxytocin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator Growth regulation Development regulation Myotropic Receptor modulation
Experimental: 6.78 minutes; /406.8 seconds; Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Oxytocin (Mus musculus): PMID 27558735##10454085 PMID27558735;10454085 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27558735/
RECORD: Rec_0303253 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]; Mus musculus [Animal]; Rattus norvegicus [Animal]
Neurohypophyseal peptide
9913; 9606; 10090; 10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
1-6
Bio-Activity Profile
Hormonal Neurobehavioral
Wistar rat plasma
3.9e-05 μM
LC-MS/MS
7.2 min
PaperPeripheral Administration of a Long-Acting Peptide Oxytocin Receptor Agonist Inhibits Fear-Induced Freezing
RECORD: Rec_0304204 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Oxytocin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Reproductive regulator Growth regulation Development regulation Myotropic Receptor modulation
smooth muscle
Experimental: 6.78 minutes; /406.8 seconds; Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Oxytocin (Mus musculus): PMID 27558735##10454085 PMID27558735;10454085 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27558735/
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