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MYP_122645
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Basic Information
Oxytocin
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Lactation-associated neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Therapeutic / Biomedical activity ▸ Enzyme replacement therapy
Standard
9 amino acids
C43H67N11O13S2
Standard
Sequence
CYIQNCPLG
Physicochemical Analysis
1010.19 Da
5.51
-0.26
-0.49
-0.0290
0.33
0.14
0.25
27.09
86.67
0.1111
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
393.74
-3.54
14.0
15.0
29.0
69.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0193216 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Oxytocin/Vasopressin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1月6日
Bio-Activity Profile
Uterotonic Obstetric Lactation-associated neuropeptide
Human oxytocin receptor
Clinical/Human: 1-6 min
PaperMolecular modeling of the oxytocin receptor/bioligand interactions PMID10698266 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10698266/
RECORD: Rec_0206542 VERIFIED: YES
Provenance & Taxonomy
Tachyglossus aculeatus aculeatus [Animal]
Oxytocin
49271
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Myotropic
causes contraction of the smooth muscle
Experimental: 6.78 minutes; /406.8 seconds; Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Oxytocin (Tachyglossus aculeatus aculeatus): PMID 4515919##10454085 PMID4515919;10454085 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4515919/
RECORD: Rec_0215593 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Oxytocin
9986
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Myotropic
causes contraction of the smooth muscle
Experimental: 6.78 minutes; /406.8 seconds; Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Oxytocin (Oryctolagus cuniculus): PMID 5150741##10454085 PMID5150741;10454085 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5150741/
RECORD: Rec_0221605 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Oxytocin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation
oxytocin receptor (OXTR)
Experimental: 6.78 minutes; /406.8 seconds; Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Oxytocin (Bos taurus): PMID 13129273##10454085 PMID13129273;10454085 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/13129273/
RECORD: Rec_0232064 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Vasopressin/Oxytocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
1-6
Bio-Activity Profile
Neuropeptide
PaperHruby V. J., Chow M., Smith D. D.. Conformational and structural considerations in oxitocin-receptor binding and biological activity. Annu. Rev. Pharmacol. Toxicol., 30, 501-534, 1990.
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