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MYP_122572
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Basic Information
Ranatuerin-2PLa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Standard
28 amino acids
C129H230N36O38S3
Standard
Sequence
GIMDTVKNVAKNLAGQLLDKLKCKITAC
Physicochemical Analysis
2989.62 Da
9.24
2.74
2.50
0.0978
0.20
0.67
0.05
3.78
115.00
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1223.45
-11.62
43.0
44.0
107.0
206.0
0.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0028009 VERIFIED: NO
Provenance & Taxonomy
Rana palustris [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0078759 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0081895 VERIFIED: YES
Provenance & Taxonomy
Rana palustris [Animal]
Ranatuerin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
25 μM
MIC
PMID11087945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087945/
RECORD: Rec_0149919 VERIFIED: YES
Provenance & Taxonomy
Pickerel frog [Animal]
Ranatuerin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial
PMID11087945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087945/
RECORD: Rec_0275327 VERIFIED: YES
Provenance & Taxonomy
Lithobates palustris [Animal]
Ranatuerin
298395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial
Escherichia coli
25 μM
MIC
PaperMultiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris. PMID11087945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087945/
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