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MYP_122539
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Basic Information
buCATHL4A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C91H132N22O15
Standard
Sequence
GLPWILLRWLFFRG
Physicochemical Analysis
1774.16 Da
12.00
1.76
1.56
0.1257
0.86
0.29
0.40
92.16
139.29
0.2857
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
588.21
2.16
22.0
17.0
52.0
128.0
7.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0195110 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
200 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0198691 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
3 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0216846 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NCDC 0111
25 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0233456 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter johnsonii NCDC 0072
200 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0241864 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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