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MYP_122497
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Basic Information
SrnA1
Antimicrobial
Standard
32 amino acids
C155H232N44O44S3
Standard
Sequence
GWFTAVQLTLAGRCGRWFTGSFECTTNNVKCG
Physicochemical Analysis
3511.96 Da
8.71
1.73
1.48
0.0541
0.02
0.62
0.12
47.11
48.75
0.1562
11000.00
11125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1434.77
-16.57
55.0
49.0
110.0
246.0
7.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0125854 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
P. gingivalis ATCC 33277
32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0190011 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S. agalactiae W73106655 or W70407881
16-32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0249648 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
E. faecium W97542221
64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0321247 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S-mutans UA159
>64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0326108 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S. pyogenes W51503011 or W80908630
16 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
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