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MYP_122497
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Basic Information
SrnA1
Antimicrobial
Standard
32 amino acids
C155H232N44O44S3
Standard
Sequence
GWFTAVQLTLAGRCGRWFTGSFECTTNNVKCG
Physicochemical Analysis
3511.96 Da
8.71
1.73
1.48
0.0541
0.02
0.62
0.12
47.11
48.75
0.1562
11000.00
11125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1434.77
-16.57
55.0
49.0
110.0
246.0
7.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022744 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
drug-resistant Enterococcus faecalis W82000259 or W80909324 or ATCC 29212
16-32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0042074 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
anti-VRE, L-rhamnosus ATCC 11981
>64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0057276 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
S. pneumoniae V4122578 or W81002644
0.5-1 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0081698 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
T. forsythia ATCC 43037
32 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
RECORD: Rec_0125587 VERIFIED: YES
Provenance & Taxonomy
Streptococcus salivarius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
it is unique that T4 is phosphorylated. Residues 9 and 19 are dehydrated. Thioether rings between residues 9 and 14, between 19 and 24, and between 21 and 31. Warning: activity was tested using salivaricin 10, a mixture of peptides (AP3698-3700)
Bio-Activity Profile
Antimicrobial
N. gonorrhoeae V3091967
64 μg/mL
MIC
PaperDiscovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.
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