Peptide Database

Peptide NameTachystatin-A 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC219H336N66O60S6

DescriptionStandard

        YSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRF
    

Molecular Weight5045.81 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.40

Charge Density (pH 7.0) 0.1295

GRAVY Index-0.24

Hydrophobic Moment 0.59

Boman Index-0.08

Instability Index36.33

Aliphatic Index 48.64

Aromaticity 0.1591

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2054.54

LogP -24.12

H-bond Donors 81.0

H-bond Acceptors 72.0

Rotatable Bonds 156.0

Heavy Atoms 351.0

Ring Count 10.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373768 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetEscherichia coli

RECORD: Rec_0381200 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0387299 VERIFIED: YES

Provenance & Taxonomy

OrganismTachypleus tridentatus [Animal]

FamilyTachystatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

Activity4.2 μg/mL

MethodIC50

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