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MYP_122493
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Basic Information
Tachystatin-A 1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
44 amino acids
C219H336N66O60S6
Standard
Sequence
YSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRF
Physicochemical Analysis
5045.81 Da
9.38
5.70
5.40
0.1295
-0.24
0.59
-0.08
36.33
48.64
0.1591
5960.00
6335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2054.54
-24.12
81.0
72.0
156.0
351.0
10.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0170616 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
Candida albicans
PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0289583 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Hemolytic
Pichia pastoris
PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0294815 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachystatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
25 μg/mL
IC50
PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0304009 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
4.2 μg/mL
IC50
PaperPubMed PMID: 10473569 PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0339565 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 29.5%, T 29.5%, C 40.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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