Peptide Database

Peptide NameSLAY-screened peptide P850

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC82H115N19O20S3

DescriptionStandard

        YQFINMCSVPFHPPC
    

Molecular Weight1783.10 Da

Isoelectric Point (pI)6.72

Net Charge (pH 7.0)-0.17

Net Charge (pH 7.4) -0.46

Charge Density (pH 7.0) -0.0116

GRAVY Index0.27

Hydrophobic Moment 0.31

Boman Index0.30

Instability Index35.88

Aliphatic Index 45.33

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 599.67

LogP -3.45

H-bond Donors 20.0

H-bond Acceptors 24.0

Rotatable Bonds 48.0

Heavy Atoms 124.0

Ring Count 7.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0209675 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/