Peptide Database

Peptide NameTat (47-57)

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC68H124N34O16

DescriptionStandard

        GYGRKKRRQRRRG
    

Molecular Weight1673.93 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.5967

GRAVY Index-3.14

Hydrophobic Moment 0.51

Boman Index-1.33

Instability Index161.72

Aliphatic Index 0.00

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 899.28

LogP -11.84

H-bond Donors 36.0

H-bond Acceptors 24.0

Rotatable Bonds 62.0

Heavy Atoms 118.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413096 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman immunodeficiency virus 1 [Virus]

FamilyTat

Tax ID11676

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermSpacer/Gly extension

C-TermGly extension

Other ModsN-term detail: Carries an extra glycine and labelled with fluores; C-term detail: Carries an extra glycine

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetTR146 cells

MethodCellular uptake assay

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