Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length102 amino acids

Chemical FormulaC497H802N140O153S13

DescriptionStandard

        MSVMKPCLMTIVILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNTCREYEIQYLTCPNDQKCCLKLSMKITSSKNVKENYDSNSNLSVANSSSYSHI
    

Molecular Weight11603.38 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.61

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0452

GRAVY Index-0.42

Hydrophobic Moment 0.55

Boman Index-0.06

Instability Index42.46

Aliphatic Index 70.69

Aromaticity 0.0686

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4773.94

LogP -54.45

H-bond Donors 171.0

H-bond Acceptors 173.0

Rotatable Bonds 390.0

Heavy Atoms 803.0

Ring Count 15.0

Amide Bonds 114.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294647 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic