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MYP_122423
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Basic Information
Grammistin Gs C
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
26 amino acids
C127H213N35O31S
Standard
Sequence
NWRKILGKIAKVAAGLLGSMLAGYQV
Physicochemical Analysis
2758.33 Da
10.46
3.76
3.55
0.1445
0.53
0.71
0.25
-6.19
127.69
0.0769
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1073.21
-7.08
38.0
36.0
94.0
194.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012868 VERIFIED: NO
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0022506 VERIFIED: YES
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Aeromonas salmonicida NCIBM 1102
25 μg/mL
MIC
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/
RECORD: Rec_0037471 VERIFIED: YES
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis IAM 1026
6.25 μg/mL
MIC
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/
RECORD: Rec_0046758 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 69.2%, E 0.0%, T 23.1%, C 7.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0056337 VERIFIED: NO
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Grammistin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Cytolytic Hemolytic Non-ribosomal
Qualitative functional evidence
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/; https://www.uniprot.org/uniprotkb/P69846/entry; https://bblserver.org.in/ampdb/
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