Peptide Database

Peptide NameApelin receptor early endogenous ligand

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC197H317N69O46S2

DescriptionStandard

        DKHGTKHDFLNLRRKYRRHNCPKKRCLPLHSRVPFP
    

Molecular Weight4452.19 Da

Isoelectric Point (pI)11.01

Net Charge (pH 7.0)9.09

Net Charge (pH 7.4) 8.64

Charge Density (pH 7.0) 0.2524

GRAVY Index-1.47

Hydrophobic Moment 0.59

Boman Index-0.51

Instability Index90.14

Aliphatic Index 51.39

Aromaticity 0.0833

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1884.35

LogP -17.68

H-bond Donors 69.0

H-bond Acceptors 61.0

Rotatable Bonds 146.0

Heavy Atoms 314.0

Ring Count 11.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0030958 VERIFIED: YES

Provenance & Taxonomy

OrganismDanio rerio [Animal]

FamilyApelin receptor early endogenous ligand

Tax ID7955

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Cardiovascular Growth regulation Development regulation Myotropic Receptor modulation

Targetmigration and development of cardiac progenitor cells

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0188646 VERIFIED: YES