Peptide Database

Peptide NameyrrS signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC184H321N57O52S

DescriptionStandard

        MSNNQSRYENRDKRRKANLVLNILIAIVSILIVVVAA
    

Molecular Weight4195.93 Da

Isoelectric Point (pI)10.93

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.28

Charge Density (pH 7.0) 0.0946

GRAVY Index0.28

Hydrophobic Moment 0.55

Boman Index-0.00

Instability Index72.27

Aliphatic Index 144.86

Aromaticity 0.0270

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1824.62

LogP -17.40

H-bond Donors 64.0

H-bond Acceptors 57.0

Rotatable Bonds 146.0

Heavy Atoms 294.0

Ring Count 1.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368609 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

MethodSecretion phenotype assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/