Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC433H695N131O131S16

DescriptionStandard

        MEHPKLYSIANLPAGRKKTQSCCKRMCVIPWQVQELAEAMSRDGAAAAREEETSAETWMLPYDVRRERYSGPVRCRYCCGCCALGVCGMCCE
    

Molecular Weight10344.99 Da

Isoelectric Point (pI)8.01

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.04

Charge Density (pH 7.0) 0.0163

GRAVY Index-0.34

Hydrophobic Moment 0.60

Boman Index-0.11

Instability Index48.22

Aliphatic Index 56.30

Aromaticity 0.0652

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4214.33

LogP -44.77

H-bond Donors 160.0

H-bond Acceptors 150.0

Rotatable Bonds 339.0

Heavy Atoms 711.0

Ring Count 14.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105083 VERIFIED: NO

Provenance & Taxonomy

OrganismScophthalmus maximus [Animal]

FamilyHepcidin

Tax ID52904

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal