Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length442 amino acids

Chemical FormulaC2236H3501N589O624S12

DescriptionStandard

        TNPGFMVRITQSGLDYAHQQGIAILEKELAQLKLPDISGDFRIQHVGKVHYEISRLDLRSFNLPYSRISLVPNVGLQVSISNAFAEVDGNWRVKIYFIRDHGSFDLKVENVYIKINLKLGSNASGKPTIDTSDCSTRISKVRVHFWGKFGWLYNLFYGAVESRFRNILESKVCENVVTSVRSELQPYLQTLPVTARIDDKAGVDYSLVAPPTATAQSLDVDLKGEFFSLAHRSTVPFPPLALAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDSVIPKGMGFHLNTSTFSAFIPQLEKMYPDMPMKLRLSAPSAPFLNIGPGGLLLKPVVDIQAYAILPSSSLAPLFLLSLTSNVSAVIDVKLGHIVGSLNMGRLRLSLKHSDVGTFQVRMLQSIMNTIASSMLLPQLNERLAEGFPLPLPDRIQLSNILVRFHQ
    

Molecular Weight49003.07 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)5.46

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.0123

GRAVY Index0.10

Hydrophobic Moment 0.72

Boman Index0.13

Instability Index37.53

Aliphatic Index 101.45

Aromaticity 0.0995

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37485.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0286831 VERIFIED: NO

Provenance & Taxonomy

OrganismSpizaetus tyrannus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria