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MYP_122231
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Basic Information
NZ16R
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
40 amino acids
C191H285N57O54S6
Standard
Sequence
GFGCNGPWNEDDLRCRNHCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
4436.05 Da
8.86
3.78
3.43
0.0946
-0.70
0.52
-0.11
14.51
29.25
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1809.89
-20.17
69.0
65.0
145.0
308.0
9.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0302152 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. pneumoniae CVCC1.8722 or CVCC2350
0.227 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0318269 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E-coli CVCC195 or CICC21530
>7.273 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0343966 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. suis CVCC3309 or CVCC3928 or CVCC606
0.014-0.028 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0360367 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-enteritidis CMCC50336
>7.273 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0367751 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. suis CVCC3928
0.014 μM
MIC
PMID31138863;28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31138863/
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