Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC166H269N51O57S2

DescriptionStandard

        KCNTATCATQRLANFLVRSSNNFGTILSSTNVGSNTY
    

Molecular Weight3955.35 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0740

GRAVY Index-0.20

Hydrophobic Moment 0.67

Boman Index-0.01

Instability Index13.82

Aliphatic Index 65.95

Aromaticity 0.0811

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1805.13

LogP -28.62

H-bond Donors 66.0

H-bond Acceptors 62.0

Rotatable Bonds 129.0

Heavy Atoms 276.0

Ring Count 3.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152418 VERIFIED: YES

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)