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MYP_122219
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Basic Information
A12L/A23L (V13KL peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C145H242N36O34
Standard
Sequence
KWKSFLKTFKSLKKTVLHTALKLISS
Physicochemical Analysis
3033.69 Da
10.78
6.84
6.58
0.2631
-0.06
0.69
-0.01
0.03
105.00
0.1154
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1159.04
-7.34
43.0
42.0
107.0
215.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020423 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa PAK
15.6 μg/mL
MIC
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0021423 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
15.6 μg/mL
MHC
Paperhttps://pubmed.ncbi.nlm.nih.gov/17158938/ PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0038324 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa PAO1
15.6 μg/mL
MIC
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0040953 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC
15.6 μg/mL
Hemolysis
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0061537 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
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