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MYP_122211
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Basic Information
Mussel Defensin MGD-1 (Mediterranean mussel defensin 1; mollusca/molluscs/mollusks, invertebrates, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
38 amino acids
C180H265N61O47S8
Standard
Sequence
GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLPCTCYRC
Physicochemical Analysis
4291.93 Da
8.94
4.94
4.46
0.1300
-0.65
0.60
-0.11
46.66
20.53
0.1316
9970.00
10470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1719.52
-20.91
69.0
63.0
129.0
296.0
12.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156083 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
4-25; 10-33; 14-35; 21-38
Hydroxylation of Trp28 (3hydroxytryptophan)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio P1
6.4 μg/mL
MIC
PMID8925841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8925841/
RECORD: Rec_0177024 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
4-25; 10-33; 14-35; 21-38
Hydroxylation of Trp28 (3hydroxytryptophan)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio splendidus
1.6 μg/mL
MIC
PMID8925841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8925841/
RECORD: Rec_0220454 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
4-25; 10-33; 14-35; 21-38
Hydroxylation of Trp28 (3hydroxytryptophan)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID8925841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8925841/
RECORD: Rec_0275386 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
4-25; 10-33; 14-35; 21-38
Hydroxylation of Trp28 (3hydroxytryptophan)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio alginolyticus
6.4 μg/mL
MIC
PMID8925841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8925841/
RECORD: Rec_0348052 VERIFIED: YES
Provenance & Taxonomy
Mytilus galloprovincialis [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
4-25; 10-33; 14-35; 21-38
Hydroxylation of Trp28 (3hydroxytryptophan)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
6.4 μg/mL
MIC
PMID8925841 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8925841/
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