Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length470 amino acids

Chemical FormulaC2319H3614N580O670S23

DescriptionStandard

        MLPPVIVMFMLVSFTCGENPAIQVTLTDKGLQYGKNVGTGWVQEKLPLVTLPDINGKIGYGIIVIDYTLTGITITKCDLPEPSVQFYQDIGGFKTSISGLSVALTGGWLTNFGIIHDGGSFNMAIFNMDLTSVVELGKDANGHLSITSVHCDAQIGDENIQFHGGASWMFQKFVDYFKGHIKGEIEGTICPYVKESIETLEYHLQAMNVSFDVAEALTFDLSLTGVPLINASSMNLGLKGELKDIKTHTDPPFEAQPFTLPEQPGYMLSMGLSEFTLNSASYGLYSAGWLKALITDSMIPSHFPVHLNTSSMGPYIPQLPKMFPGLLMNLQIYARELPMFSFHPGVVKLGFQGAAKAFAIQPNGTQTPLFKLNVDSEFSGKVQIVGGRLNGSISLDNYTLTLAASEVGAFKTDALERFTRAGMMMALSKLNGSLRKGVDLPRMRHAQLVNTVLSVKEGFIAVFSDAQVLI
    

Molecular Weight51076.48 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-9.54

Net Charge (pH 7.4) -10.47

Charge Density (pH 7.0) -0.0203

GRAVY Index0.17

Hydrophobic Moment 0.74

Boman Index0.21

Instability Index24.43

Aliphatic Index 94.79

Aromaticity 0.0957

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009670 VERIFIED: NO

Provenance & Taxonomy

OrganismSander lucioperca [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence