Peptide Database

Peptide NameCyclotide psyle F

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC137H224N36O40S6

DescriptionStandard

        GVIPCGESCVFIPCITAAVGCSCKNKVCYKN
    

Molecular Weight3207.85 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0548

GRAVY Index0.69

Hydrophobic Moment 0.26

Boman Index0.24

Instability Index27.50

Aliphatic Index 81.61

Aromaticity 0.0645

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1201.20

LogP -13.21

H-bond Donors 46.0

H-bond Acceptors 48.0

Rotatable Bonds 101.0

Heavy Atoms 219.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166520 VERIFIED: YES

Provenance & Taxonomy

OrganismPsychotria leptothyrsa [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidemultiple disulfide bonds reported, sites not specified

Bio-Activity Profile

Function

Cytotoxic

RECORD: Rec_0353548 VERIFIED: NO