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MYP_122189
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Basic Information
pAntp (43-58)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C104H168N34O20S
Standard
Sequence
RQIKIWFQNRRMKWKK
Physicochemical Analysis
2246.73 Da
12.00
6.76
6.55
0.4223
-1.73
0.38
-0.62
46.60
48.75
0.1875
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
950.45
-5.08
35.0
28.0
80.0
159.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0172598 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
[Refer PubMed ID - 23029273: Xanthomonas axonopodis pv. glycines (
32 μM
MIC
PMID23029273;26860980;23085001;28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23029273/
RECORD: Rec_0174905 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: 6-Maleimidocaproic acid derivative linker
Bio-Activity Profile
Imaging
PaperShuttle-Cargo Fusion Molecules of Transport Peptides and the hD2/3 Receptor Antagonist Fallypride: A Feasible Approach To Preserve Ligand-Receptor Binding? Evidence URLhttps://doi.org/10.1021/jm5004123
RECORD: Rec_0176489 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperPreferential uptake of L- versus D-amino acid cell-penetrating peptides in a cell type-dependent manner PMID21867915 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21867915/
RECORD: Rec_0176494 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Labelled with fluoresceine
Bio-Activity Profile
Cell-penetrating peptide
MDCK cells
Fluorescence-based uptake assay
PMID15290867 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15290867/
RECORD: Rec_0179864 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
[Refer PubMed ID - 23029273: Xanthomonas axonopodis pv. glycines (
7 μM
MIC
PMID23029273;26860980;23085001;28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23029273/
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