Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC417H665N115O116S8

DescriptionStandard

        MKTNFFLSSAVRIAVLLFAIFFFMSQVLPGNKINLEICERPDGSCRDFCLETEIHVGRCLNSRPCCLPLGHQPRIESTTPKKD
    

Molecular Weight9401.96 Da

Isoelectric Point (pI)8.29

Net Charge (pH 7.0)1.63

Net Charge (pH 7.4) 1.21

Charge Density (pH 7.0) 0.0197

GRAVY Index0.06

Hydrophobic Moment 0.46

Boman Index0.04

Instability Index52.31

Aliphatic Index 88.07

Aromaticity 0.0843

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3688.86

LogP -33.84

H-bond Donors 132.0

H-bond Acceptors 128.0

Rotatable Bonds 308.0

Heavy Atoms 656.0

Ring Count 15.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326190 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal