Peptide Database

Peptide NameDefensin beta 118 (Beta-defensin 118) (Epididymal secretory protein 13.6) (ESP13.6)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC590H954N170O184S8

DescriptionStandard

        MKLLLLALPILVLLPQVIPAYGGEKKCWNRSGHCRKQCKDGEAVKETCKNHRACCVPSNEDHRRLPTTSPTPLSDSTPGIIDNILTIRFTTDYFEISSKKDMVEESEAGQGTQTSPPNVHHTS
    

Molecular Weight13629.44 Da

Isoelectric Point (pI)7.64

Net Charge (pH 7.0)0.90

Net Charge (pH 7.4) 0.30

Charge Density (pH 7.0) 0.0073

GRAVY Index-0.53

Hydrophobic Moment 0.52

Boman Index-0.08

Instability Index58.47

Aliphatic Index 75.28

Aromaticity 0.0407

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5665.69

LogP -64.03

H-bond Donors 199.0

H-bond Acceptors 198.0

Rotatable Bonds 448.0

Heavy Atoms 952.0

Ring Count 21.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390122 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyBeta-defensin; Defensin

Tax ID9544

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

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