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MYP_122151
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Basic Information
Defensin beta 118 (Beta-defensin 118) (Epididymal secretory protein 13.6) (ESP13.6)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
123 amino acids
C590H954N170O184S8
Standard
Sequence
MKLLLLALPILVLLPQVIPAYGGEKKCWNRSGHCRKQCKDGEAVKETCKNHRACCVPSNEDHRRLPTTSPTPLSDSTPGIIDNILTIRFTTDYFEISSKKDMVEESEAGQGTQTSPPNVHHTS
Physicochemical Analysis
13629.44 Da
7.64
0.90
0.30
0.0073
-0.53
0.52
-0.08
58.47
75.28
0.0407
8480.00
8855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
5665.69
-64.03
199.0
198.0
448.0
952.0
21.0
131.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042516 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Beta-defensin; Defensin
9544
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli
PMID11564719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11564719/
RECORD: Rec_0112214 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Beta-defensin; Defensin
9544
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Bacillus subtilis
PMID11564719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11564719/
RECORD: Rec_0133317 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Beta-defensin; Defensin
9544
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Salmonella Typhimurium
PMID11564719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11564719/
RECORD: Rec_0142068 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Beta-defensin; Defensin
9544
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PMID11564719 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11564719/
RECORD: Rec_0187660 VERIFIED: NO
Provenance & Taxonomy
Macaca fascicularis [Animal]
Defensin
9541
Structure & Mods
linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic
Qualitative functional evidence
Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22002653/
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