Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length466 amino acids

Chemical FormulaC2307H3729N601O644S20

DescriptionStandard

        MHLWCWLALVAFIPVTSSTSPGVKVKITEKGLEYGKQIGMVTLQQKLKAIKVPDISGTQKVAPIGKVRYSLSKMQIMNLGLPKSALTLAPGTGVSLSISNAFINLHGNWKVKYMNFIKDSGSFDLSVNGLTITTSISVKSDETGRPVVNSVNCGATVGSAKIKFHGGASWLYNLFSKFIDQALRKALQKQICPLVADAISELNPHLKTLNVLAKVDKLAEIEYSMVSSPVISKSSIDLSLKGEFYNIGQHQEPPFSPKPFPMPPQVNNMLYIGVSTFTINSAAFVYNKAGALSLFITDDMIPPSSPIRLNTRTFGAFIPQIAKRFPGLMMKLLVKTVKDPGITLEGNNVTVQTTSTVTAYAIQPNSTLTPLFILNVDISVSARMYLTEMRLAGAVALNTMDMNLRTSYVGDFQVRPLQNIFQIVLKVAVIPRVNAQFQKGCPLPAIGKMKLVNSQLQVLKVRHSVI
    

Molecular Weight50830.23 Da

Isoelectric Point (pI)9.85

Net Charge (pH 7.0)23.98

Net Charge (pH 7.4) 23.31

Charge Density (pH 7.0) 0.0515

GRAVY Index0.17

Hydrophobic Moment 0.80

Boman Index0.15

Instability Index32.72

Aliphatic Index 103.09

Aromaticity 0.0751

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0276342 VERIFIED: NO

Provenance & Taxonomy

OrganismMyripristis murdjan [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria