Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC280H440N74O91S5

DescriptionStandard

        MKNTNIIDIEATNALQELSFEELDTIIGAKKKGNDGAIPTISHDCHMNSWQFIFTCCS
    

Molecular Weight6459.26 Da

Isoelectric Point (pI)4.73

Net Charge (pH 7.0)-4.34

Net Charge (pH 7.4) -4.72

Charge Density (pH 7.0) -0.0749

GRAVY Index-0.18

Hydrophobic Moment 0.36

Boman Index0.08

Instability Index28.27

Aliphatic Index 80.86

Aromaticity 0.0690

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2672.56

LogP -28.65

H-bond Donors 92.0

H-bond Acceptors 94.0

Rotatable Bonds 218.0

Heavy Atoms 450.0

Ring Count 8.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262266 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus ovuberis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria