MYP_122127
Basic Information
ACTH analogue- 4
Steroidogenic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XYSMEHFRYGKPVGKKRR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0045409 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACTH
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
βAla = Beta alanine
Bio-Activity Profile
Steroidogenic
Rat muscle slices, in vitro; 5292 s
RECORD: Rec_0184690 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACTH
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Ibu = α-aminoisobutyric acid
Bio-Activity Profile
Steroidogenic
Intravenously injected to rat, in vivo; 199.2 s
RECORD: Rec_0267519 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACTH
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Ibu = α-aminoisobutyric acid
Bio-Activity Profile
Steroidogenic
native hormone but subcutaneous potency was rather low (264U/mg) and in vitro potency was much lower (83U/mg) than the intravenous and intramuscular potencies
Intravenously injected to rat, in vivo; 576 s