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MYP_122111
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Basic Information
L5K5W2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C71H127N17O12
Standard
Sequence
KWLKKLLKKLL
Physicochemical Analysis
1410.87 Da
10.60
4.76
4.54
0.4323
-0.13
0.78
-0.13
-10.56
177.27
0.0909
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
500.21
1.85
18.0
17.0
53.0
100.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004566 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 10031
2 μg/mL
MIC
PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
RECORD: Rec_0030789 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA-TK784
2 μg/mL
MIC
PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
RECORD: Rec_0063504 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
2 μg/mL
MIC
PaperStructural characterization of de novo designed L5K5W model peptide isomers with potent antimicrobial and varied hemolytic activities. Molecules. 2013 Jan 11;18(1):859-876. doi: 10.3390/molecules18010859. PMID: 23344198. PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
RECORD: Rec_0079617 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0113418 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Shigella dysenteriae ATCC 9752
1 μg/mL
MIC
PaperStructural characterization of de novo designed L5K5W model peptide isomers with potent antimicrobial and varied hemolytic activities. Molecules. 2013 Jan 11;18(1):859-876. doi: 10.3390/molecules18010859. PMID: 23344198. PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
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